Deep Dive Article

Why the Mouse Lived Longer and You Probably Won't

A 12% lifespan gain in a lab mouse is thrilling, reproducible, and almost never transferable — and taurine is the newest name on a very long list.

Every Ashwagandha Trial Seems to Work. That's the Problem.

You're Probably Not Magnesium Deficient. You Might Still Be Short.

Around half of us eat too little magnesium — yet no ordinary blood test can tell you whether you're truly short. That gap, between intake and proof, is the whole business model.

The Vitamin D Trials Didn't Fail. They Tested the Wrong People.

Three giant trials, three null results — and why that's the most reassuring news in the field, not the most damning.

The Salt Argument Is Really an Argument About Who You Are

Two camps, both right about their own person and wrong to generalise. The methodology fight, the sweat-sodium maths, and a decision map you can actually find yourself on.

The Cold Plunge Works by Cancelling the Adaptation You Came For

Less soreness doesn't buy more growth — the trials already tested the objection everyone raises. Here's the answer, and the decision map by training goal

Bryan Johnson's Best Result Is the One He Doesn't Lead With

The DunedinPACE number is the headline. The bloods are the proof. Telling them apart is the whole game.

The Weight-Loss Drug That Cut Heart Attacks — and Failed at Alzheimer's

What "weight-independent benefit" actually means, and the honest line between treating ageing and treating the diseases it causes.

What the WHI Got Wrong

And what the November 2025 re-analysis still won't fix — including the "50% heart attack reduction" the headlines are now claiming.

When More Testosterone Made Bones Weaker

It is worth being precise about what the fracture finding does and doesn’t do.

Sauna Buys You Vascular Health — Not Fitness

Five trials in people who don't move at all, what they actually showed, and the only condition under which the wooden box does anything that resembles training.

The Grey Peptide Economy

How a $80 vial of BPC-157 leaves a Hebei industrial park and arrives in a Crouch End bathroom cabinet — and why the FDA crackdown didn't slow it down.

The Sleep Stage Ageing Takes First— and the Pill That Makes It Worse

Why the most restorative sleep stage quietly disappears, why the most-prescribed sleep drug accelerates the loss, and what the evidence says actually protects it.